| Meaning | Saint James |
| Origin | Latin, Spanish |
| Gender | Boy |
| Popularity | Popular |
| Length | 8 |
| Syllables | 4 |
| Syllabification | San-ti-a-go |
Santiago pulses with cultural richness and timeless elegance. This name travels beautifully across borders, recognized and respected in Spanish-speaking communities worldwide while gaining substantial popularity among English speakers who appreciate its melodic quality. The name flows smoothly, its three syllables creating a rhythmic pattern that feels both substantial and graceful. Santiago brings sophisticated European flair without pretension, offering nickname options like Santi or Iago for more casual settings. Its strong presence in literature, history, and geography—from the Camino de Santiago pilgrimage route to South American capitals—imbues it with depth and significance. The name balances warmth with authority, making it suitable for someone destined to be both approachable and accomplished. Its increasing popularity reflects broader appreciation for Hispanic heritage and multicultural identity.
| Samuel |
| Sebastian |
| Simon |
| Solomon |
| Silas |
| Spencer |
| Sawyer |
| Sidney |
| Sullivan |
| Sterling |
| Scott |
| Shane |
| Sant |
| Santi |
| Tiago |
| Ago |
| Tia |
| Santiago Ramón y Cajal | Spanish neuroscientist and Nobel laureate |
| Santiago Calatrava | Spanish architect and engineer |
| Santiago Bernabeu | Spanish footballer and president of Real Madrid |
| Santiago Cabrera | Chilean-British actor |
| Santiago Segura | Spanish film director and actor |
| Santiago Solari | Argentine former footballer and manager |
| Santiago Moreno | Colombian footballer |
| Santiago Giraldo | Colombian tennis player |
| Santiago Luna | Spanish professional golfer |
| Santiago "Jimmy" Vega | Protagonist in the "Inspector Santiago" book series |
| Santiago Munez | Protagonist in the film series "Goal!" |
| Santiago "Santi" Montoya | Character in the TV series "Narcos" |
| Santiago Herrera | Character in the TV series "One Tree Hill" |
| Santiago "Nino" Vargas | Character in the film "City of God" |
| Santiago Rodriguez | Character in the TV series "Brooklyn Nine-Nine" |
| Santiago Batista | Character in the film "Old" |
| Santiago "Cisco" Ramon | Character in the TV series "The Flash" |
| Santiago Muñez | Character in the film "Sueño" |
| Santiago "Saint" Matamoros | Character in the video game "Red Dead Redemption II" |