| Meaning | valley of the wolves, river of the wolf |
| Origin | Spanish |
| Gender | gender neutral |
| Opposite gender | Guadalupe |
| Popularity | Moderate |
| Length | 9 |
| Syllables | 4 |
| Syllabification | Gua-da-lu-pe |
Rich in cultural significance and musical in pronunciation, Guadalupe carries the weight of tradition with remarkable grace. This name resonates deeply within Hispanic communities, connecting children to generations of heritage and faith. The four syllables create a rhythmic pattern that's both lyrical and substantial, giving the name a presence that commands attention. Guadalupe works equally well in Spanish and English-speaking contexts, offering children the gift of bilingual ease. While traditionally associated with girls in some regions, its use for boys remains strong and meaningful in many communities, particularly when honoring family members or religious devotion. The name's length and complexity make it distinctive in any setting, ensuring your son will be the only Guadalupe in most rooms. It speaks to parents who value their roots, who want their children to carry forward cultural identity with pride, and who aren't afraid of names that require a bit more effort to pronounce. Guadalupe is powerful, unapologetic, and deeply meaningful.
| Lupe |
| Guadalup |
| Guadelupe |
| Guadelup |
| Guadaloupe |
| Guadaloup |
| Guadalupo |
| Guadalupito |
| Lalo |
| Lupito |
| Gabriel |
| Guillermo |
| Gustavo |
| Gael |
| Gonzalo |
| Gino |
| Giovanni |
| Giuseppe |
| Gerard |
| Gilbert |
| Gerardo |
| Griffin |
| Lupe |
| Guad |
| Guady |
| Lup |
| Loopy |
| Guadalupe Victoria | 1786–1843 - First President of Mexico |
| Guadalupe Pineda | born 1955 - Mexican singer |
| Guadalupe Olivo | born 1961 - Mexican boxer |
| Guadalupe Plata | born 1982 - Spanish musician |
| Guadalupe Larriva | born 1956 - Ecuadorian politician |
| Guadalupe Berrío | born 1971 - Colombian footballer |
| Guadalupe Reyes | born 1977 - Mexican baseball player |
| Guadalupe Day | born 1969 - Belizean footballer |
| Guadalupe Pérez | born 1995 - Argentine footballer |
| Guadalupe González | born 1989 - Mexican racewalker |
| Guadalupe Rosales | born 1980 - American artist |
| Guadalupe Ruiz | born 1962 - Mexican long-distance runner |
| Guadalupe Urbina | born 1983 - Costa Rican singer-songwriter |
| Guadalupe "Lupillo" Rivera | born 1972 - Mexican-American singer |
| Guadalupe Marengo | born 1973 - Argentine human rights activist |
| Guadalupe Hidalgo | 1785–1850 - Mexican lawyer and politician |
| Guadalupe Leija Sánchez | born 1972 - Mexican politician |
| Guadalupe Morcillo | born 1961 - Argentine historian |
| Guadalupe Ríos | born 1992 - Chilean footballer |
| Guadalupe de la Cruz | born 1970 - Mexican footballer |
| Guadalupe "Lupe" Garcia | Character in the movie "Mi Vida Loca" |
| Guadalupe Romero | Character in the novel "All the Pretty Horses" by Cormac McCarthy |
| Guadalupe Gomez | Character in the TV show "East Los High" |
| Guadalupe "Lupito" | Character in the novel "Bless Me, Ultima" by Rudolfo Anaya |
| Guadalupe "Lupe" Rojas | Character in the video game "Borderlands" |
| Guadalupe "Lupe" Ontiveros | Character in the TV show "Weeds" |
| Guadalupe "Lupe" Perez | Character in the movie "American Me" |
| Guadalupe "Lupe" Gutierrez | Character in the TV show "Ugly Betty" |